Rare Psychiatry News
Advertisement
5 Facts you should know about
Wolfram syndrome
1
Diabetes mellitus is typically the first manifestation, usually diagnosed around age 6
2
The observation of optic nerve atrophy after the diagnosis of diabetes mellitus is often a clue to the diagnosis
3
Urinary tract problems affect 60 to 90 % of patients
4
Most patients die prematurely with severe neurological disabilities
5
The median age at death is approximately 30 years, usually from respiratory failure as a result of brain stem atrophy